- % Scrimmage Event
- Event times are (CST)
| August |
| | 27 | 12:00PM | Robert Morris College | @ | Mayville State | 18-21 | |
| September |
| | 2 | 6:00PM | Mayville State | @ | University of Minnesota-Crookston | 29-31 | |
| | 10 | 2:00PM | Trinity Bible College | @ | Mayville State | 6-65 | |
| | 17 | 1:30PM | Mayville State | @ | Gustavus Adolphus | 9-6 | |
| * | 24 | 1:00PM | Jamestown | @ | Mayville State | 35-13 | |
| October |
| * | 1 | 2:30PM | Mayville State | @ | Dickinson State | 14-47 | |
| | 8 | 2:00PM | Valley City | @ | Mayville State | 52-20 | |
| * | 15 | 1:00PM | Mayville State | @ | Jamestown | 12-28 | |
| | Homecoming | |
| * | 22 | 1:00PM | Dickinson State | @ | Mayville State | 14-15 | |
| | 29 | 1:00PM | Mayville State | @ | Valley City | 14-28 | |
| November |
| | 5 | 2:00PM | Dakota State | @ | Mayville State | 0-6 | |
% Exhibition/Scrimmage Event
Event times are ()
